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vineri, 14 septembrie 2012

'Individualismul' biochimic




Biochimia individuala si necesarul de nutrienti

In cartea sa “Individualitatea biochimica” Roger Williams – biochimist si nutritionist- spune ca necesarul pt un anume nutrient poate varia de la o persoana la alta foarte mult.
Nutrientii esentiali sant substante pe care organismul nu le poate produce. Luand in considerare dieta total dezechilibrata, superprocesata si aditivata a zilelor noastre, este mai mult decat evident ca ea determina multe dintre bolile cronice cu care ne confruntam. Vestea buna e ca,tot prin dieta si siplimentarea ei la nevoie si personalizat,putem sa si intervenim asupra lor.
Relatia nutrienti-genom are dublu-sens: necesarul nutritional este dependent genetic iar nutrientii influenteaza stabilitatea genomului; ei actioneaza ca antioxidanti si co-factori in metabolismul si reparatiile AND-ului.
Modificarile genetice datorate chiar unei deficiente nutritionale moderate pot rivaliza cu cele determinate de factorii de mediu cunoscuti cancerigeni (radiatii, substante chimice, etc).
Dupa cum foarte sugestiv spune profesor-doctor Gheorghe Mencinicopschi: “suntem ceea ce mancam dar si ceea ce NU mancam”.


In his book, Biochemical Individuality, biochemist and nutrition pioneer Roger Williams showed that requirements for any given nutrient may vary from person to person. These exceptional needs might be due to differences in digestion, absorption, excretion, enzyme patterns or other causes.
Essential nutrients are substances that the body cannot make, or cannot make in adequate amounts. Given the sad state of today's diet, it is more than likely that many of our chronic "lifestyle" diseases are the result of dietary shortcomings and will; therefore, respond to dietary interventions.Unmet nutritional needs will sooner or later lead to health problems.
Not only do nutrient requirements depend on genetic individuality but nutrients in turn are crucial for genome stability; they act as antioxidants and co-factors for enzymes involved in DNA metabolism and repair. In fact, genome damage caused by even moderate micronutrient deficiencies rivals damage from environmental factors like chemical carcinogens or radiation.

Sources:

Roger J. Williams, Biochemical individuality, John Wiley & Sons, 1963





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